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Referee Comments: Referee 1

Posted by PLOS_ONE_Group on 02 Sep 2007 at 22:50 GMT

Reviewer 1's Review

“Previous literature on cost effectiveness studies in Mexico is limited. Given the limitations, the authors have done a thorough job in explaining the face validity of the assumptions obtained from several worldwide sources.

However, some information on prior approaches employed for cost effectiveness can help in strengthening the paper's claims over previous analyses.

CEA is sensitive to the choice of strategies compared. A major strength of the paper is in the choice of strategies that you have made that are very appealing to clinicians and policy makers.”

N.B. These are the general comments made by the reviewer when reviewing the originally submitted version of this paper. The manuscript was revised before publication. Specific minor points addressed during revision of the paper are not shown.