Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population

Dong-Yi Chen; Chao-Yung Wang; Ming-Shien Wen; Tsong-Hai Lee; Yen Chu; Ming-Jer Hsieh; Shang-Hung Chang; Cheng-Hung Lee; Jian-Liang Wang; Chun-Chi Chen; Laing-Suei Lu; Ming-Ta Lee; San-Jou Yeh; Fun-Chiung Lin; I-Chang Hsieh

doi:10.1371/journal.pone.0039178

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Peer-reviewed

Research Article

Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population

Dong-Yi Chen ,

Contributed equally to this work with: Dong-Yi Chen, Chao-Yung Wang

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Chao-Yung Wang ,

Contributed equally to this work with: Dong-Yi Chen, Chao-Yung Wang

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Ming-Shien Wen,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Tsong-Hai Lee,

Affiliation Stroke Center and Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Yen Chu,

Affiliation Division of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Ming-Jer Hsieh,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Shang-Hung Chang,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Cheng-Hung Lee,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Jian-Liang Wang,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Chun-Chi Chen,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Laing-Suei Lu,

Affiliation Institute of Biomedical Sciences, Academia Sinica, Taiwan
⨯
Ming-Ta Lee,

Affiliation Institute of Biomedical Sciences, Academia Sinica, Taiwan
⨯
San-Jou Yeh,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
Fun-Chiung Lin,

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯
I-Chang Hsieh

* E-mail: ocean.laboratory@me.com

Affiliation Second Section of Cardiology, Department of Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
⨯

Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population

Dong-Yi Chen,
Chao-Yung Wang,
Ming-Shien Wen,
Tsong-Hai Lee,
Yen Chu,
Ming-Jer Hsieh,
Shang-Hung Chang,
Cheng-Hung Lee,
Jian-Liang Wang,
Chun-Chi Chen

Published: June 18, 2012
https://doi.org/10.1371/journal.pone.0039178

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Citations?

Posted by dansette on 23 Jun 2012 at 09:29 GMT

The following papers should have been cited :
1: Dansette PM, Rosi J, Bertho G, Mansuy D. Paraoxonase-1 and clopidogrel efficacy. Nat Med. 2011 Sep 7;17(9):1040-1; author reply 1042-4. doi: 10.1038/nm.2436. PubMed PMID: 21900914.
2: Dansette PM, Rosi J, Bertho G, Mansuy D. Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer. Chem Res Toxicol. 2012 Feb20;25(2):348-56. Epub 2011 Dec 1. PubMed PMID: 22103858.

In addition that other paper which appeared just before the submission:
3: Gong IY, Crown N, Suen CM, Schwarz UI, Dresser GK, Knauer MJ, Sugiyama D, Degorter MK, Woolsey S, Tirona RG, Kim RB. Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet
response. Eur Heart J. 2012 Feb 27. [Epub ahead of print] PubMed PMID: 22374717.

No competing interests declared.

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Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population

Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population

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Citations?

Posted by dansette on 23 Jun 2012 at 09:29 GMT