Site and Strain-Specific Variation in Gut Microbiota Profiles and Metabolism in Experimental Mice

Open Access

Peer-reviewed

Research Article

Melissa K. Friswell,

Affiliation Microbiology Research Group, School of Pharmacy and Pharmaceutical Sciences, The University of Manchester, Manchester, United Kingdom
⨯
Helen Gika,

Affiliations AstraZeneca, Department of Clinical Pharmacology, Drug Metabolism and Pharmacokinetics, Macclesfield, United Kingdom, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
⨯
Ian J. Stratford,

Affiliation Experimental Oncology Research Group, School of Pharmacy and Pharmaceutical Sciences, The University of Manchester, Manchester, United Kingdom
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Georgios Theodoridis,

Affiliations AstraZeneca, Department of Clinical Pharmacology, Drug Metabolism and Pharmacokinetics, Macclesfield, United Kingdom, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
⨯
Brian Telfer,

Affiliation Experimental Oncology Research Group, School of Pharmacy and Pharmaceutical Sciences, The University of Manchester, Manchester, United Kingdom
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Ian D. Wilson,

Affiliation AstraZeneca, Department of Clinical Pharmacology, Drug Metabolism and Pharmacokinetics, Macclesfield, United Kingdom
⨯
Andrew J. McBain

* E-mail: andrew.mcbain@manchester.ac.uk

Affiliation Microbiology Research Group, School of Pharmacy and Pharmaceutical Sciences, The University of Manchester, Manchester, United Kingdom
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Reader Comments

No competing interests declared.

Mouse models
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Drug metabolism
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Genetics
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Gut bacteria
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Clustering algorithms
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Genetic fingerprinting
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Denaturing gradient gel electrophoresis
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Metabolites
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