Measurements of CFTR-Mediated Cl⁻ Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis

• Marisa Sousa ,

  Contributed equally to this work with: Marisa Sousa, Maria F. Servidoni

  Affiliations BioFIG - Centre for Biodiversity, Functional and Integrative Genomics; Faculty of Sciences, University of Lisboa, Lisboa, Portugal, Department of Genetics - National Institute of Health, Lisboa, Portugal

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• Maria F. Servidoni ,

  Contributed equally to this work with: Marisa Sousa, Maria F. Servidoni

  Affiliations Gastrocentro - Endoscopy Unit - State University of Campinas, Campinas, Brazil, Pediatrics Department - State University of Campinas, Campinas, Brazil

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• Adriana M. Vinagre,

  Affiliation Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil

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• Anabela S. Ramalho,

  Affiliations BioFIG - Centre for Biodiversity, Functional and Integrative Genomics; Faculty of Sciences, University of Lisboa, Lisboa, Portugal, Department of Genetics - National Institute of Health, Lisboa, Portugal

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• Luciana C. Bonadia,

  Affiliation Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil

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• Verónica Felício,

  Affiliation BioFIG - Centre for Biodiversity, Functional and Integrative Genomics; Faculty of Sciences, University of Lisboa, Lisboa, Portugal

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• Maria A. Ribeiro,

  Affiliation CIPED - Research Center in Pediatrics - State University of Campinas, Campinas, Brazil

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• Inna Uliyakina,

  Affiliations BioFIG - Centre for Biodiversity, Functional and Integrative Genomics; Faculty of Sciences, University of Lisboa, Lisboa, Portugal, Department of Genetics - National Institute of Health, Lisboa, Portugal

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• Fernando A. Marson,

  Affiliation Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil

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• Arthur Kmit,

  Affiliation Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil

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• Silvia R. Cardoso,

  Affiliations Pediatrics Department - State University of Campinas, Campinas, Brazil, Endoscopy Unit – University Hospital of Campinas, Campinas, Brazil

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• José D. Ribeiro,

  Affiliations Pediatrics Department - State University of Campinas, Campinas, Brazil, Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil, CIPED - Research Center in Pediatrics - State University of Campinas, Campinas, Brazil

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• Carmen S. Bertuzzo,

  Affiliation Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil

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• Lisete Sousa,

  Affiliation CEAUL - Center of Statistics and Applications of the University of Lisboa; Department of Statistics and Operation Research, Faculty of Sciences, University of Lisboa, Lisboa, Portugal

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• Karl Kunzelmann,

  Affiliation Institut für Physiologie – University of Regensburg, Regensburg, Germany

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• Antônio F. Ribeiro,

  Affiliations Pediatrics Department - State University of Campinas, Campinas, Brazil, Faculty of Medical Sciences - State University of Campinas, Campinas, Brazil, CIPED - Research Center in Pediatrics - State University of Campinas, Campinas, Brazil

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•  [ ... ],
• Margarida D. Amaral

  * E-mail: mdamaral@fc.ul.pt

  Affiliations BioFIG - Centre for Biodiversity, Functional and Integrative Genomics; Faculty of Sciences, University of Lisboa, Lisboa, Portugal, Department of Genetics - National Institute of Health, Lisboa, Portugal

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