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Referee Comments: Referee 1

Posted by PLOS_ONE_Group on 24 Oct 2007 at 16:38 GMT

Reviewer 1's Review

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This manuscript is excellent. All phases of the trial are thoroughly described: conception, design, conduct, analysis and report. This reviewer would like to congratulate the authors for their very innovative trial.

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N.B. These are the general comments made by the reviewer when reviewing this paper in light of which the manuscript was revised. Specific points addressed during revision of the paper are not shown.