A Live-Attenuated HSV-2 ICP0− Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine

William P. Halford; Ringo Püschel; Edward Gershburg; Andrew Wilber; Svetlana Gershburg; Brandon Rakowski

doi:10.1371/journal.pone.0017748

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Peer-reviewed

Research Article

A Live-Attenuated HSV-2 ICP0⁻ Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine

William P. Halford ,

* E-mail: halford@siumed.edu

Affiliation Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America
⨯
Ringo Püschel,

Affiliation Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America
⨯
Edward Gershburg,

Affiliation Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America
⨯
Andrew Wilber,

Affiliation Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America
⨯
Svetlana Gershburg,

Affiliation Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America
⨯
Brandon Rakowski

Affiliation Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America
⨯

A Live-Attenuated HSV-2 ICP0⁻ Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine

William P. Halford,
Ringo Püschel,
Edward Gershburg,
Andrew Wilber,
Svetlana Gershburg,
Brandon Rakowski

Published: March 11, 2011
https://doi.org/10.1371/journal.pone.0017748

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Media Coverage of this Article

Posted by PLOS_ONE_Group on 30 Nov 2011 at 10:42 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: The State Journal Register
Title: “Follow-up file: Researcher’s herpes vaccine work meets resistance - Springfield, IL - The State Journal-Register”
http://www.sj-r.com/top-s...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

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A Live-Attenuated HSV-2 ICP0⁻ Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine

A Live-Attenuated HSV-2 ICP0⁻ Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine

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Media Coverage of this Article

Posted by PLOS_ONE_Group on 30 Nov 2011 at 10:42 GMT