Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country

Emma K. Nickerson; Vanaporn Wuthiekanun; Gumphol Wongsuvan; Direk Limmathurosakul; Pramot Srisamang; Weera Mahavanakul; Janjira Thaipadungpanit; Krupal R. Shah; Arkhom Arayawichanont; Premjit Amornchai; Aunchalee Thanwisai; Nicholas P. Day; Sharon J. Peacock

doi:10.1371/journal.pone.0006512

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Open Access

Peer-reviewed

Research Article

Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country

Emma K. Nickerson ,

* E-mail: emma@tropmedres.ac

Affiliations Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand, Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
⨯
Vanaporn Wuthiekanun,

Affiliation Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
⨯
Gumphol Wongsuvan,

Affiliation Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
⨯
Direk Limmathurosakul,

Affiliation Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
⨯
Pramot Srisamang,

Affiliation Department of Paediatrics, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand
⨯
Weera Mahavanakul,

Affiliation Department of Medicine, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand
⨯
Janjira Thaipadungpanit,

Affiliation Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
⨯
Krupal R. Shah,

Affiliation Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Arkhom Arayawichanont,

Affiliation Department of Medicine, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand
⨯
Premjit Amornchai,

Affiliation Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
⨯
Aunchalee Thanwisai,

Affiliation Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
⨯
Nicholas P. Day,

Affiliations Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand, Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
⨯
Sharon J. Peacock

Affiliations Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand, Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯

Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country

Emma K. Nickerson,
Vanaporn Wuthiekanun,
Gumphol Wongsuvan,
Direk Limmathurosakul,
Pramot Srisamang,
Weera Mahavanakul,
Janjira Thaipadungpanit,
Krupal R. Shah,
Arkhom Arayawichanont,
Premjit Amornchai

Published: August 4, 2009
https://doi.org/10.1371/journal.pone.0006512

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I appreciate the conclusion about PVL...

Posted by shearer on 28 Aug 2009 at 21:24 GMT

It's worthwhile to know in general what PVL is predictive of, but it's also just as worthwhile to have the clarity to see that it does not provide clinically relevant information at the moment.

No competing interests declared.

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Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country

Factors Predicting and Reducing Mortality in Patients with Invasive Staphylococcus aureus Disease in a Developing Country

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I appreciate the conclusion about PVL...

Posted by shearer on 28 Aug 2009 at 21:24 GMT