Towards a Physiology-Based Measure of Pain: Patterns of Human Brain Activity Distinguish Painful from Non-Painful Thermal Stimulation

Justin E. Brown; Neil Chatterjee; Jarred Younger; Sean Mackey

doi:10.1371/journal.pone.0024124

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Peer-reviewed

Research Article

Towards a Physiology-Based Measure of Pain: Patterns of Human Brain Activity Distinguish Painful from Non-Painful Thermal Stimulation

Justin E. Brown,

Affiliations Department of Anesthesia, Stanford University, Palo Alto, California, United States of America, Neurosciences Program, Stanford University, Palo Alto, California, United States of America, Department of Biology and Environmental Science, Simpson College, Indianola, Iowa, United States of America
⨯
Neil Chatterjee,

Affiliations Department of Anesthesia, Stanford University, Palo Alto, California, United States of America, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
⨯
Jarred Younger,

Affiliation Department of Anesthesia, Stanford University, Palo Alto, California, United States of America
⨯
Sean Mackey

* E-mail: smackey@pain.stanford.edu

Affiliations Department of Anesthesia, Stanford University, Palo Alto, California, United States of America, Neurosciences Program, Stanford University, Palo Alto, California, United States of America
⨯

Towards a Physiology-Based Measure of Pain: Patterns of Human Brain Activity Distinguish Painful from Non-Painful Thermal Stimulation

Justin E. Brown,
Neil Chatterjee,
Jarred Younger,
Sean Mackey

Published: September 13, 2011
https://doi.org/10.1371/journal.pone.0024124

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 16 Sep 2011 at 18:07 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Medical News Today
Title: “Tool That Measures Pain Objectively Under Way”
http://www.medicalnewstod...

Publication: El Mundo.es
Title: “Más cerca del 'dolorímetro' perfecto | Neurociencia | elmundo.es”
http://www.elmundo.es/elm...

Publication: CNN Blogs
Title: “Researchers closer to developing a ‘pain-o-meter’ – The Chart - CNN.com Blogs”
http://thechart.blogs.cnn...

Publication: Press Release
Title: “Does that hurt? Objective way to measure pain being developed at Stanford- Office of Communications & Public Affairs - Stanford University School of Medicine”
http://med.stanford.edu/i...

Publication: Top News Arab Emirates
Title: “Computer to Voice Human Pain! | TopNews Arab Emirates”
http://topnews.ae/content...

Publication: i09
Title: “An objective way to measure pain? It's closer than you think.”
http://io9.com/5839517/an...

Publication: Technology Review
Title: “An Objective Way to Measure Pain - Technology Review”
http://www.technologyrevi...

Publication: Top News United States
Title: “Pain Transforms from Subjective To Objective Manner | TopNews United States”
http://topnews.us/content...

Publication: Red Orbit
Title: “Computer Algorithm Can Sense Pain - Health News - redOrbit”
http://www.redorbit.com/n...

Publication: Scope Stanford University School of Medicine
Title: “Stanford scientists work towards developing a “painometer” - Scope - medical blog - Stanford University School of Medicine”
http://scopeblog.stanford...

Publication: Voice of America
Title: “OUCH! Developing a Machine that Measures Pain - Science World”
http://blogs.voanews.com/...

Publication: Zee News India
Title: “Coming soon: `A way to measure pain`”
http://zeenews.india.com/...

Publication: Reuters
Title: “Feeling pain? The computer can tell | Reuters”
http://www.reuters.com/ar...

Publication: The Vancouver Sun
Title: “Researchers developing tool to precisely measure pain”
http://www.vancouversun.c...

Publication: ZDNet Health
Title: “Training computers to help detect pain | ZDNet”
http://www.zdnet.com/blog...

Publication: CNN Blogs
Title: “Researchers closer to developing a pain-o-meter - The Chart - CNN.com Blogs”
http://thechart.blogs.cnn...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: Media Coverage of This Article

PLOS_ONE_Group replied to PLOS_ONE_Group on 23 Sep 2011 at 20:18 GMT

Additional media coverage that has occurred for this paper:

Publication: The Atlantic
Title: “A New, Objective Way to Study Pain - Alice G. Walton - Life - The Atlantic”
http://www.theatlantic.co...

Publication: Scientific American
Title: “Scientists Find a New Way to Measure Pain: Scientific American Podcast”
http://www.scientificamer...

Publication: Ivanhoe Newswire
Title: “The Pain-o-meter: Seeing Pain | Medical News and Health Information”
http://search.ivanhoe.com...

Publication: Health News Digest
Title: “HealthNewsDigest.com”
http://www.healthnewsdige...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: RE: Media Coverage of This Article

PLOS_ONE_Group replied to PLOS_ONE_Group on 21 Dec 2012 at 21:53 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Stanford School of Medicine
Title: “Researchers report progress in quest to create objective method of detecting pain- Office of Communications & Public Affairs - Stanford University School of Medicine- Office of Communications & Public Affairs - Stanford University School of Medicine”
http://med.stanford.edu/i...

Publication: American News Report
Title: “Stanford Researchers Find New Way to Diagnose Pain | American News Report”
http://americannewsreport...

Publication: San Francisco Business Times
Title: “Gain in pain: Stanford researchers use brain scans, algorithms to ID chronic pain patients - San Francisco Business Times”
http://www.bizjournals.co...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

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Towards a Physiology-Based Measure of Pain: Patterns of Human Brain Activity Distinguish Painful from Non-Painful Thermal Stimulation

Towards a Physiology-Based Measure of Pain: Patterns of Human Brain Activity Distinguish Painful from Non-Painful Thermal Stimulation

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 16 Sep 2011 at 18:07 GMT

RE: Media Coverage of This Article

PLOS_ONE_Group replied to PLOS_ONE_Group on 23 Sep 2011 at 20:18 GMT

RE: RE: Media Coverage of This Article

PLOS_ONE_Group replied to PLOS_ONE_Group on 21 Dec 2012 at 21:53 GMT