Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice

Alison K. Bauer; Hye-Youn Cho; Laura Miller-DeGraff; Christopher Walker; Katherine Helms; Jennifer Fostel; Masayuki Yamamoto; Steven R. Kleeberger

doi:10.1371/journal.pone.0026590

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Peer-reviewed

Research Article

Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice

Alison K. Bauer ,

Contributed equally to this work with: Alison K. Bauer, Hye-Youn Cho

* E-mail: alison.bauer@ucdenver.edu

Affiliation Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan , United States of America
⨯
Hye-Youn Cho ,

Contributed equally to this work with: Alison K. Bauer, Hye-Youn Cho

Affiliation Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Laura Miller-DeGraff,

Affiliation Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Christopher Walker,

Affiliation Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Katherine Helms,

Affiliation Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan , United States of America
⨯
Jennifer Fostel,

Affiliation Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Masayuki Yamamoto,

Affiliation Division of Medical Biochemistry, Graduate School of Medicine, Tohoku University, Sendai, Japan
⨯
Steven R. Kleeberger

Affiliation Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯

Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice

Alison K. Bauer,
Hye-Youn Cho,
Laura Miller-DeGraff,
Christopher Walker,
Katherine Helms,
Jennifer Fostel,
Masayuki Yamamoto,
Steven R. Kleeberger

Published: October 21, 2011
https://doi.org/10.1371/journal.pone.0026590

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Publisher's Note: Error in Table 1

Posted by PLOS_ONE_Group on 02 Nov 2011 at 21:11 GMT

treatment.
http://plosone.org/article/info:doi/10.1371/journal.pone.0026590#pone-0026590-t001

Table 1 Clusters are from "Figure 6B" not from "Figure 7A."

No competing interests declared.

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Lung and intrathoracic tumors
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Secondary lung tumors
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Urethanes
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Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice

Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice

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Publisher's Note: Error in Table 1

Posted by PLOS_ONE_Group on 02 Nov 2011 at 21:11 GMT