Anti-Inflammatory Preconditioning by Agonists of Adenosine A1 Receptor

Sigal Nakav; Cidio Chaimovitz; Yuval Sufaro; Eli C. Lewis; Gad Shaked; David Czeiger; Moshe Zlotnik; Amos Douvdevani

doi:10.1371/journal.pone.0002107

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Open Access

Peer-reviewed

Research Article

Anti-Inflammatory Preconditioning by Agonists of Adenosine A1 Receptor

Sigal Nakav,

Affiliation Department of Clinical Biochemistry, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
Cidio Chaimovitz,

Affiliation Department of Nephrology, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
Yuval Sufaro,

Affiliation Department of Clinical Biochemistry, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
Eli C. Lewis,

Affiliation Department of Clinical Biochemistry, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
Gad Shaked,

Affiliation Department of General Surgery, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
David Czeiger,

Affiliation Department of General Surgery, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
Moshe Zlotnik,

Affiliation Department of Nephrology, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯
Amos Douvdevani

* E-mail: amosd@bgu.ac.il

Affiliations Department of Clinical Biochemistry, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel, Department of Nephrology, Soroka Medical University Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯

Anti-Inflammatory Preconditioning by Agonists of Adenosine A1 Receptor

Sigal Nakav,
Cidio Chaimovitz,
Yuval Sufaro,
Eli C. Lewis,
Gad Shaked,
David Czeiger,
Moshe Zlotnik,
Amos Douvdevani

Published: May 7, 2008
https://doi.org/10.1371/journal.pone.0002107

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Referee Comments: Referee 2

Posted by PLOS_ONE_Group on 12 May 2008 at 17:51 GMT

Referee 2's review:

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N.B. These are the comments made by the referee when reviewing an earlier version of this paper. Prior to publication, the manuscript has been revised in light of these comments and to address other editorial requirements.
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New data with PTX and an A1 receptor antagonist appear to confirm the hypothesis presented by the authors.

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Adenosine
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Inflammation
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White blood cells
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Peritonitis
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Inflammatory diseases
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Gene expression
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Anti-Inflammatory Preconditioning by Agonists of Adenosine A1 Receptor

Anti-Inflammatory Preconditioning by Agonists of Adenosine A1 Receptor

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Referee Comments: Referee 2

Posted by PLOS_ONE_Group on 12 May 2008 at 17:51 GMT